(+)-PENTAZOCINE-DEA SCHEDULE IV ITEM
Names
[ CAS No. ]:
7361-76-4
[ Name ]:
(+)-PENTAZOCINE-DEA SCHEDULE IV ITEM
[Synonym ]:
PENTAZOCINE, (+)-
2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-buten-1-yl)-, (2S,6S,11S)-
(1S,9S,13S)-1,13-Dimethyl-10-(3-methyl-2-buten-1-yl)-10-azatricyclo[7.3.1.02,7]trideca-2,4,6-trien-4-ol
(2S,6S,11S)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol
A2G9VU2P2J
PENTAZOCINE
cis-(+)-pentazocine
(+)-pentazocine
EINECS 206-634-6
α-(+)-Pentazocine
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
403.5±45.0 °C at 760 mmHg
[ Molecular Formula ]:
C19H27NO
[ Molecular Weight ]:
285.424
[ Flash Point ]:
180.8±27.4 °C
[ Exact Mass ]:
285.209259
[ LogP ]:
4.53
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.554
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ RIDADR ]:
NONH for all modes of transport
Articles
Br. J. Pharmacol. 172 , 4052-65, (2015)
Application of orthosteric sigma-1 receptor agonists as anti-seizure drugs has been hindered by questionable efficacy and potential adverse effects. Here, we have investigated the anti-seizure effects...
Involvement of hypothalamic neuropeptide Y in pentazocine induced suppression of food intake in rats.Neuropeptides 48(3) , 133-41, (2014)
The potent orexigenic peptide neuropeptide Y (NPY) has been considered as a possible endogenous ligand for a subpopulation of sigma receptors (SigR). However, their mutual interaction with reference t...
Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.J. Med. Chem. 57(24) , 10404-23, (2014)
The discovery and synthesis of a new series of pyrimidines as potent sigma-1 receptor (σ1R) antagonists, associated with pharmacological antineuropathic pain activity, are the focus of this article. T...