Schnurri-3 inhibitor-1

Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC50 value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis[1].

Research Areas >> Others

Signaling Pathways >> Others >> Others

Schnurri-3[1]

Schnurri-3 inhibitor-1 (0-50 μM; 24 h) can inhibit Shn3 with EF1alpha promoter in SV40 large T antigen-transformed osteoblast cell line (Clone20-Shn3FFL) with an AC50 value of 2.09 μM[1]. Schnurri-3 inhibitor-1 (0.195-26 μM; 48 h) exhibits moderate activity in HepG2 mammalian cells with an AC50 value of 54.73 μM[1]. Cell Viability Assay[1] Cell Line: Clone20-Shn3FFL cells Concentration: 2.09 μM Incubation Time: 24 hours Result: Showed the active concentration AC50 value of 2.09 μM. Cell Viability Assay[1] Cell Line: Clone20-Shn3FFL cells Concentration: 1.2 μM Incubation Time: 24 hours Result: Showed the active concentration AC50 value of 1.2 μM.

[1]. National Center for Biotechnology Information. PubChem Compound Summary for CID 2473445.