Meclocycline Sulfosalicylate Salt

Names

[ Name ]:
Meclocycline Sulfosalicylate Salt

[Synonym ]:
1,3,2-Dioxaborolane,2-(3-chloro-5-methylphenyl)-4,4,5,5-tetramethyl
MeClC6H3CH2B(pin)
3-chloro-5-methylphenylpinacolborane
Meclocycline 2-hydroxy-5-sulfobenzoic acid
MeClC6H3B(pinacolato)
meclocycline 5-sulfosalicylate
1-chloro-3-methylphenyl-5-BPin
meclocycline sulfosalicylate

Biological Activity

[Description]:

Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic with broad-spectrum antibacterial activities, preventing skin bacterial infections such as acne vulgaris[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Bacterial[1]

[References]

[1]. Knutson DD, et al. Meclocycline sulfosalicylate. Topical antibiotic agent for the treatment of acne vulgaris. Cutis. 1981 Feb;27(2):203-4, 208-10.

Chemical & Physical Properties

[ Boiling Point ]:
716.4ºC at 760 mmHg

[ Molecular Formula ]:
C₂₉H₂₇ClN₂O₁₄S

[ Molecular Weight ]:
695.04800

[ Flash Point ]:
387.1ºC

[ Exact Mass ]:
694.08700

[ PSA ]:
301.90000

[ LogP ]:
2.33370

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

Topical antibiotics in dermatology.

Arch. Dermatol. 124 , 1691-1700, (1988)

Topical antibiotics are safe and effective in certain conditions, primarily acne, rosacea, and nasal carriage of Staphylococcus aureus. They are useful in impetigo only when it is of limited extent. T...

The use of antibiotics in acne therapy: oral or topical administration?

J. Antimicrob. Chemother. 10 , 89-115, (1982)

Topical v systemic agent treatment for papulopustular acne. A cost-effectiveness analysis.

Arch. Dermatol. 120 , 1571-1578, (1984)

We used cost-effectiveness analysis to compare the costs, risks, and benefits of two strategies for clearing papulopustular acne; topical therapy alone as initial therapy or a combination of systemic ...