N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide

Names

[ Name ]:
N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide

[Synonym ]:
N,N,N',N',-Tetracyclohexyl-3-oxapentandiamin
N,N,N',N'-TETRACYCLOHEXYL-3-OXAPENTANEDIAMIDE
ETH 129

Biological Activity

[Description]:

N,N,N′,N′-Tetracyclohexyl-3-oxapentanediamide (Calcium ionophore II) is a lipophilic ionophore that can be used in preparing calcium ion-selective electrode[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Calcium ion-selective electrode can be used to measure the intracellular free calcium[1].

[References]

[1]. Ma YL, et, al. A study of calcium ion-selective PVC membrane electrode based on neutral carrier N,n,n',n'-tetracyclo-3-oxapentanediamide (correction of oxapetanediamide). J Tongji Med Univ. 1992;12(2):98-102.

Chemical & Physical Properties

[ Density]:
1.07g/cm3

[ Boiling Point ]:
613.7ºC at 760 mmHg

[ Molecular Formula ]:
C₂₈H₄₈N₂O₃

[ Molecular Weight ]:
460.69

[ Flash Point ]:
325ºC

[ Exact Mass ]:
460.36600

[ PSA ]:
49.85000

[ LogP ]:
5.99100

[ Index of Refraction ]:
1.536

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
37

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Indo-1 binding to protein in permeabilized ventricular myocytes alters its spectral and Ca binding properties.

Biophys. J. 63(1) , 89-97, (1992)

We have examined the binding of the fluorescent Ca indicator indo-1 to cellular protein in permeabilized ventricular myocytes and also to soluble and particulate myocyte protein. Using either a filtra...

Ion-selective electrode for measuring low Ca2+ concentrations in the presence of high K+, Na+ and Mg2+ background.

Anal. Chem. 69 , 1061-1069, (1997)

In this work, ion-selective electrodes for calcium ion were investigated. Two ionophores were used in the membranes: ETH 1001 and ETH 129. An internal filling solution buffered for primary ion was use...

Induction of a non-specific permeability transition in mitochondria from Yarrowia lipolytica and Dipodascus (Endomyces) magnusii yeasts.

J. Bioenerg. Biomembr. 41(3) , 239-49, (2009)

In this study we used tightly-coupled mitochondria from Yarrowia lipolytica and Dipodascus (Endomyces) magnusii yeasts, possessing a respiratory chain with the usual three points of energy conservatio...