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(6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic Acid

Names

[ CAS No. ]:
7444-29-3

[ Name ]:
(6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic Acid

Biological Activity

[Description]:

Anhydroleucovorin is a form of tetrahydrofolate and is a substrate for cyclohydrolase, which converts it to 10-formyltetrahydrofolate. Anhydroleucovorin can be used for research in the field of tumors[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. M J OSBORN, et al. Participation of anhydroleucovorin in the hydroxymethyl tetrahydrofolic dehydrogenase system. Biochim Biophys Acta,1957,26, 3.  

[2]. K Motycka, et al. Localized chemotherapy of Gardner's lymphosarcoma of C3H mice using combinations of carrier-sorbed antifolics and detoxicating tetrahydrofolates. Czech Med,1981,4, 1.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H21N7O6

[ Molecular Weight ]:
455.42

[ Exact Mass ]:
456.16300

[ PSA ]:
193.75000

[ LogP ]:
0.52040

Related Compounds