1-(2-Chloroethyl)-3-(2,6-dideoxy-1,3,4-tri-O-acetyl-D-glucopyranos-2-yl)-1-nitrosourea
Names
[ CAS No. ]:
74729-54-7
[ Name ]:
1-(2-Chloroethyl)-3-(2,6-dideoxy-1,3,4-tri-O-acetyl-D-glucopyranos-2-yl)-1-nitrosourea
[Synonym ]:
1-(2-Chloroethyl)-3-(2,6-dideoxy-1-O,3-O,4-O-triacetyl-D-glucopyranos-2-yl)-1-nitrosourea
Chemical & Physical Properties
[ Density]:
1.49g/cm3
[ Molecular Formula ]:
C15H22ClN3O9
[ Molecular Weight ]:
423.80300
[ Exact Mass ]:
423.10400
[ PSA ]:
149.90000
[ LogP ]:
0.84900
[ Index of Refraction ]:
1.567
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS4906070
- CHEMICAL NAME :
- Urea, 1-(2-chloroethyl)-3-(2,6-dideoxy-1,3,4-tri-O-acetyl-D -glucopyranos-2-yl)-1 -nitroso-
- CAS REGISTRY NUMBER :
- 74729-54-7
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H22-Cl-N3-O9
- MOLECULAR WEIGHT :
- 423.85
- WISWESSER LINE NOTATION :
- T6OTJ BOV1 CMVNNO&2G DOV1 EOV1 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1095,1980