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Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((tetrahydro-2H-pyran-2-yl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)- (9CI)

Names

[ CAS No. ]:
751-73-5

[ Name ]:
Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((tetrahydro-2H-pyran-2-yl)oxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)- (9CI)

[Synonym ]:
11,17-dimethoxy-18-tetrahydropyran-2-yloxy-yohimbane-16-carboxylic acid methyl ester
Su-7064

Chemical & Physical Properties

[ Density]:
1.27g/cm3

[ Boiling Point ]:
638.9ºC at 760 mmHg

[ Molecular Formula ]:
C28H38N2O6

[ Molecular Weight ]:
498.61100

[ Flash Point ]:
340.2ºC

[ Exact Mass ]:
498.27300

[ PSA ]:
82.25000

[ LogP ]:
3.76940

[ Index of Refraction ]:
1.608

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZF9800000
CHEMICAL NAME :
3-beta,20-alpha-Yohimban-16-beta-carboxylic acid, 11-alpha,17-alpha-dimethoxy-18-beta- (tetrahydro-2-pyranyloxy)-, methyl ester
CAS REGISTRY NUMBER :
751-73-5
LAST UPDATED :
199012
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C28-H38-N2-O6
MOLECULAR WEIGHT :
498.68
WISWESSER LINE NOTATION :
T F6 D5 C666 EM ON&&TTTJ HO1 TO1 UVO1 SO- BT6OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
173 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,112,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,112,1972

Related Compounds