L-(+)-Leucinol

Names

[ Name ]:
L-(+)-Leucinol

[Synonym ]:
(2S)-2-Amino-4-methyl-1-pentanol
H-LEU-OL
(S)-(+)-2-Amino-4-Methyl-1-Pentanol
L-Leu-ol
(S)-leucinol
L-(S)-leucinol
EINECS 231-400-5
(S)-2-Amino-4-methylpentanol
(2S)-2-amino-4-methylpentanol
L-LEUCINOL
1-Pentanol, 2-amino-4-methyl-, (2S)-
H-L-LEU-OL
(S)-(+)-Leucinol
(2S)-2-amino-4-methylpentan-1-ol
(S)-2-amino-4-methylpentan-1-ol
leucinol
1-Pentanol, 2-amino-4-methyl-, (S)-
MFCD00063676
H-LEUCINOL
(S)-2-amino-4-methyl-1-pentanol
(1S)-1-(hydroxymethyl)-3-methylbutylamine
EINECS 231-400-5

Biological Activity

[Description]:

L-Leucinol ((+)-Leucinol) is a competitive aminopeptidase inhibitor with Ki value of 17 μM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> Aminopeptidase

Chemical & Physical Properties

[ Density]:
0.917

[ Boiling Point ]:
208-210 ºC

[ Melting Point ]:
66 - 70ºC

[ Molecular Formula ]:
C₆H₁₅NO

[ Molecular Weight ]:
117.189

[ Flash Point ]:
90 ºC

[ Exact Mass ]:
117.115364

[ PSA ]:
46.25000

[ LogP ]:
0.45

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.4496-1.4516

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ WGK Germany ]:
3

[ HS Code ]:
2922199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922199090

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Pharmaceuticals and Surfactants from Alga-Derived Feedstock: Amidation of Fatty Acids and Their Derivatives with Amino Alcohols.

ChemSusChem 8 , 2670-80, (2015)

Amidation of renewable feedstocks, such as fatty acids, esters, and Chlorella alga based biodiesel, was demonstrated with zeolites and mesoporous materials as catalysts and ethanolamine, alaninol, and...

Chiral bis(amino alcohol)oxalamide gelators-gelation properties and supramolecular organization: racemate versus pure enantiomer gelation.

Chemistry 9(22) , 5567-80, (2003)

Four new chiral bis(amino alcohol)oxalamides (1-4: amino alcohol=leucinol, valinol, phenylglycinol, and phenylalaninol, respectively) have been prepared as low-molecular-weight organic gelators. Their...

A colorimetric chiral sensor based on chiral crown ether for the recognition of the two enantiomers of primary amino alcohols and amines.

Chirality 23(4) , 349-53, (2011)

A new colorimetric chiral sensor material consisting of three different functional sites such as chromophore (2,4-dinitrophenylazophenol dye), binding site (crown ether), and chiral barrier (3,3'-diph...