1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyridinyl)-1-piperazinyl)-, dihydrochloride
Names
[ CAS No. ]:
75449-08-0
[ Name ]:
1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyridinyl)-1-piperazinyl)-, dihydrochloride
[Synonym ]:
1-(4-Methyl-2-(methylthio)-1,3-thiazol-5-yl)-3-(4-(2-pyridinyl)-1-piperazinyl)-1-propanone
Chemical & Physical Properties
[ Density]:
1.3g/cm3
[ Boiling Point ]:
568.5ºC at 760 mmHg
[ Molecular Formula ]:
C17H23ClN4OS2
[ Molecular Weight ]:
398.97400
[ Flash Point ]:
297.6ºC
[ Exact Mass ]:
398.10000
[ PSA ]:
102.87000
[ LogP ]:
3.76830
[ Index of Refraction ]:
1.646
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UC3081300
- CHEMICAL NAME :
- 1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyrid inyl)-1-piperazinyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 75449-08-0
- LAST UPDATED :
- 198712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H22-N4-O-S2.2Cl-H
- MOLECULAR WEIGHT :
- 435.47
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 36,545,1979