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m-PEG8-NHS ester

Names

[ CAS No. ]:
756525-90-3

[ Name ]:
m-PEG8-NHS ester

[Synonym ]:
AmbotzPEG1885
4,7,10,13,16,19,22,25-Octaoxahexacosanoic Acid N-Succinimidyl Ester
N-Succinimidyl 4,7,10,13,16,19,22,25-Octaoxahexacosanoate
M2187
MeO-dPEG(8)-NHS
Methyl-PEG8-NHS Ester

Biological Activity

[Description]:

m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Inflammation/Immunology

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. By Boehnke, et al. Preparation of antibody drug conjugates with NAMPT inhibitors for use in treatment of cancer. Patent WO2019149637A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H39NO12

[ Molecular Weight ]:
509.54500

[ Exact Mass ]:
509.24700

[ PSA ]:
137.52000

Related Compounds