Fmoc-N-amido-PEG8-acid

Names

[ Name ]:
Fmoc-N-amido-PEG8-acid

[Synonym ]:
5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28-nonaoxa-4-azahentriacontan-31-oic acid
Fmoc-N-amido-PEG8-acid

Biological Activity

[Description]:

Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Fulcher JM, et al. Chemical synthesis of Shiga toxin subunit B using a next-generation traceless "helping hand" solubilizing tag. Org Biomol Chem. 2019 Dec 28;17(48):10237-10244.

Chemical & Physical Properties

[ Density]:
1.190±0.06 g/cm3

[ Molecular Formula ]:
C₃₄H₄₉NO₁₂

[ Molecular Weight ]:
663.75200

[ Exact Mass ]:
663.32500

[ PSA ]:
149.47000

[ LogP ]:
3.52350

[ Storage condition ]:
2-8°C， Seal

[ Water Solubility ]:
Slightly soluble (2.5 g/L) (25 ºC)

Fmoc-N-amido-PEG8-acid

Names

Biological Activity

Chemical & Physical Properties

Related Compounds