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NH2-PEG9-acid

Names

[ CAS No. ]:
756526-04-2

[ Name ]:
NH2-PEG9-acid

[Synonym ]:
1-Amino-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid
MFCD11041146
3,6,9,12,15,18,21,24-Octaoxaheptacosan-27-oic acid, 1-amino-
H2N-PEG8-COOH

Biological Activity

[Description]:

NH2-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

[References]

[1]. Michael Nathaniel ALONSO, et al. Antibody adjuvant conjugates. WO2018009916A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
547.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H39NO10

[ Molecular Weight ]:
441.514

[ Flash Point ]:
284.7±30.1 °C

[ Exact Mass ]:
441.257385

[ LogP ]:
-3.36

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.470

Related Compounds