(S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

Names

[ Name ]:
(S)-(-)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl

[Synonym ]:
2,2'-Bis(diphenylphosphanyl)-1,1'-binaphthalene
Phosphine, 1,1'-[1,1'-binaphthalene]-2,2'-diylbis[1,1-diphenyl-
rac-2,2'-Bis-(diphenylphosphino)-1,1'-binaphthyl
1,1'-binaphthalene-2,2'-diylbis(diphenylphosphane)
(±)-BINAP
1,1'-Binaphthalen-2,2'-diylbis(diphenylphosphan)
1,1'-Binaphthalene-2,2'-diylbis(diphenylphosphine)
rac-binap
UNII:OX12238KWH
(r)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl
BINAP
[1,1'-Binaphthalene]-2,2'-diylbis[diphenylphosphine]
MFCD00010805
UNII:970O8508MB
UNII:4F1X2F8NA3

Biological Activity

[Description]:

(S)-BINAP is the inactive isomer of (R)-BINAP (HY-W017757), and can be used as an experimental control. (R)-BINAP is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Nathalia Azevedo Portilho, et al. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells.

[2]. Keystone Symposia 2019 - Epigenetics and Human Disease

Chemical & Physical Properties

[ Boiling Point ]:
724.3±55.0 °C at 760 mmHg

[ Melting Point ]:
239-242ºC

[ Molecular Formula ]:
C₄₄H₃₂P₂

[ Molecular Weight ]:
622.67

[ Flash Point ]:
419.0±37.8 °C

[ Exact Mass ]:
622.197937

[ PSA ]:
27.18000

[ LogP ]:
13.38

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
-235 ° (C=0.3， Toluene)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

On the mechanism of an asymmetric alpha,beta-unsaturated carboxylic acid hydrogenation: application to the synthesis of a PGD2 receptor antagonist.

J. Am. Chem. Soc. 128 , 17063, (2006)

Ruthenium complexes employing axially chiral ligands were found to be effective asymmetric hydrogenation catalysts for the reduction of alpha,beta-unsaturated ene acid 1-E to give 2, a prostaglandin D...

The preparation of bi-functional organophosphine oxides as potential antitumor agents.

Eur. J. Med. Chem. 45 , 5527-30, (2010)

Following our previously reported pyridinyl phosphine oxides as antitumor agents, we targeted the commercially available C(2)-axial chiral organophosphine ligand catalysts, such as 2,2'-bis(diphenylph...

Ohkuma, T. et al.

J. Am. Chem. Soc. 117 , 2675, (1995)