Dihydrocurcumin

Names

[ Name ]:
Dihydrocurcumin

Biological Activity

[Description]:

Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Yu Q, et al. Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. Biomed Pharmacother. 2018 Jul;103:1327-1336.

Chemical & Physical Properties

[ Density]:
1.277g/cm3

[ Boiling Point ]:
616.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₂O₆

[ Molecular Weight ]:
370.39600

[ Flash Point ]:
217.8ºC

[ Exact Mass ]:
370.14200

[ PSA ]:
96.22000

[ LogP ]:
3.77200

[ Index of Refraction ]:
1.634

[ Storage condition ]:
2-8℃

Dihydrocurcumin

Names

Biological Activity

Chemical & Physical Properties

Related Compounds