Ligustrazine Hydrochloride

Names

[ Name ]:
Ligustrazine Hydrochloride

[Synonym ]:
Pyrazine, tetramethyl-, hydrochloride
Pyrazine, 2,3,5,6-tetramethyl-, hydrochloride (1:1)
tetramethylpyrazine hydrochloride
T6N DNJ B1 C1 E1 F1 &&HCl
Ligustrazine hydrochloride
2,3,5,6-tetramethylpyrazine hydrochloride
Tetramethylpyrazine hydrochloride (1:1)
Ligustrazine HCl,hydrochloride
Ligustrazine Hydrochloride

Biological Activity

[Description]:

Ligustrazine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Ligustrazine hydrochloride displayed a protection effect on injured ECV304 cells, NOS and NO formation were significantly increased compared with the model group [1].In vivo:

[Related Catalog]:

Signaling Pathways >> Others >> Others

Natural Products >> Alkaloid

Research Areas >> Others

[References]

[1]. Xu D, et al. Protective effect of ligustrazine hydrochloride on homocysteine-injured ECV304 cells. Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(12):1836-9.

[2]. Wang Q, et al. Brain microdialysate, CSF and plasma pharmacokinetics of ligustrazine hydrochloride in rats after intranasal and intravenous administration. Biopharm Drug Dispos. 2013 Oct;34(7):417-22.

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
192.7ºC at 760mmHg

[ Molecular Formula ]:
C₈H₁₂N₂

[ Molecular Weight ]:
136.19

[ Flash Point ]:
71.6ºC

[ PSA ]:
25.78000

[ LogP ]:
2.51220

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2942000000

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%