Lactofen

Names

[ Name ]:
Lactofen

[Synonym ]:
lactofen [ANSI]
cobraherbicide
COBRA(R)
yl-2-oxoethylester
1-Ethoxy-1-oxo-2-propanyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate
ppg844
2-Ethoxy-1-methyl-2-oxoethyl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate
cobra (tm)
MFCD01632761
COBRA
1'-(Carboethoxy)ethyl 5-[2-chloro-4-(trifluoromethyl)-phenoxy]-2-nitrobenzoate
Benzoic acid, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitro-, 2-ethoxy-1-methyl-2-oxoethyl ester
2-(2-nitro-5-(2-chloro-4-trifluoromethylphenoxy)benzoyloxy)propanoic acid ethyl ester
FXFFR CG DOR DNW CVOY1&VO2
rac-(2R)-1-ethoxy-1-oxopropan-2-yl 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoate
1'-(ethoxycarbonyl)ethyl 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate
Phoenix
Lactofen
ethyl O-[5-(2-chloro-α,α,α-trifluoro-p-tolyloxy)-2-nitrobenzoyl]-DL-lactate

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
494.0±45.0 °C at 760 mmHg

[ Melting Point ]:
43.9 - 45.5 degreesºC

[ Molecular Formula ]:
C₁₉H₁₅ClF₃NO₇

[ Molecular Weight ]:
461.773

[ Flash Point ]:
252.6±28.7 °C

[ Exact Mass ]:
461.048920

[ PSA ]:
107.65000

[ LogP ]:
4.84

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.535

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG5643120

CHEMICAL NAME :: Benzoic acid, 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitro-, 2-ethoxy-1-methyl-2- oxoethyl ester

CAS REGISTRY NUMBER :: 77501-63-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H15-Cl-F3-N-O7

MOLECULAR WEIGHT :: 461.80

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C77,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C77,1991

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H312-H411

[ Precautionary Statements ]:
P273-P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn,N

[ Risk Phrases ]:
21-51/53

[ Safety Phrases ]:
36/37-61

[ RIDADR ]:
UN3077 9/PG 3

[ RTECS ]:
DG5643120

[ HS Code ]:
2918990025

Customs

[ HS Code ]: 2918990025

Articles

Enantioselective degradation in sediment and aquatic toxicity to Daphnia magna of the herbicide lactofen enantiomers.

J. Agric. Food Chem. 58(4) , 2439-45, (2010)

Many pesticides in use are chiral compounds containing stereoisomers. However, the environmental behavior and fate of such compounds with respect to enantioselectivity so far has received little atten...

A codon deletion confers resistance to herbicides inhibiting protoporphyrinogen oxidase.

Proc. Natl. Acad. Sci. U. S. A. 103(33) , 12329-34, (2006)

Herbicides that act by inhibiting protoporphyrinogen oxidase (PPO) are widely used to control weeds in a variety of crops. The first weed to evolve resistance to PPO-inhibiting herbicides was Amaranth...

Influence of soil properties on the enantioselective dissipation of the herbicide lactofen in soils.

J. Agric. Food Chem. 57(13) , 5865-71, (2009)

A scheme was developed to elucidate the dissipation behaviors of the two enantiomers of the herbicide lactofen in soils using a normal-phase high-performance liquid chromatograph (HPLC) with UV detect...