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GNF5-amido-Me

Names

[ CAS No. ]:
778277-37-5

[ Name ]:
GNF5-amido-Me

Biological Activity

[Description]:

PROTAC ABL binding moiety 2, the GNF5 (ABL inhibitor) moiety, binds to IAP ligand via a linker to form SNIPER[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₁₅F₃N₄O₂

[ Molecular Weight ]:
388.34

[ Storage condition ]:
2-8°C