Bis-PEG6-acid

Names

[ Name ]:
Bis-PEG6-acid

Biological Activity

[Description]:

PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> PROTAC >> PROTAC

[Target]

PROTAC linker[1]

[References]

[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₆O₁₀

[ Molecular Weight ]:
354.35

Safety Information

[ Hazard Codes ]:
Xi

Bis-PEG6-acid

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds