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Sophocarpine hydrobromide

Names

[ CAS No. ]:
78003-71-1

[ Name ]:
Sophocarpine hydrobromide

[Synonym ]:
Sophocarpine,hydrobromide
13,14-Didehydromatridin-15-one hydrobromide
Matridin-15-one,13,14-didehydro-,monohydrobromide

Chemical & Physical Properties

[ Molecular Formula ]:
C15H23BrN2O

[ Molecular Weight ]:
327.26000

[ Exact Mass ]:
326.09900

[ PSA ]:
23.55000

[ LogP ]:
2.48160

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WG1137000
CHEMICAL NAME :
Sophocarpine, hydrobromide
CAS REGISTRY NUMBER :
78003-71-1
LAST UPDATED :
198602
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C15-H22-N2-O.Br-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
298 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 11,555,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
73640 ug/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 11,555,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
101 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
REFERENCE :
CTYAD8 Zhongcaoyao. Chinese Traditional and Herbal Medicine. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.11- 1980- Volume(issue)/page/year: 11,555,1980

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