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ADTL-SA1215

Names

[ CAS No. ]:
782387-91-1

[ Name ]:
ADTL-SA1215

Biological Activity

[Description]:

ADTL-SA1215 is a first-in-class specific small-molecule activator of SIRT3 that modulates autophagy in triple negative breast cancer.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin

[References]

[1]. Zhang J, et al. Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer. J Med Chem. 2021 Oct 14;64(19):14192-14216.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H29I2NO3

[ Molecular Weight ]:
657.32


Related Compounds