Bonnecor
Names
[ CAS No. ]:
78816-67-8
[ Name ]:
Bonnecor
[Synonym ]:
Ethyl (5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(B,F)azepin-3-yl)carbamate monohydrochloride
Carbamic acid,(5-((dimethylamino)acetyl)-10,11-dihydro-5H-dibenz(B,F)azepin-3-yl)-,ethyl ester,monohydrochloride
TIRACIZINEHYDROCHLORIDE
AWD-19-166
Tiracizine Hydrochioride
3-Carbethoxyamino-5-dimethylaminoacetyl-10,11-dihydrodibenz(B,F)azepine hydrochloride
GS-015
5H-Dibenz(B,F)azepine-3-carbamic acid,10,11-dihydro-5-((dimethylamino)acetyl)-,ethyl ester,monohydrochloride
3-Carbethoxyamino-5-dimethylaminoacetyl-iminodibenzyle-Hydrochlorid
Chemical & Physical Properties
[ Boiling Point ]:
525.3ºC at 760 mmHg
[ Molecular Formula ]:
C21H26ClN3O3
[ Molecular Weight ]:
403.90200
[ Flash Point ]:
271.5ºC
[ Exact Mass ]:
403.16600
[ PSA ]:
61.88000
[ LogP ]:
4.51990
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- HN8110000
- CHEMICAL NAME :
- 5H-Dibenz(b,f)azepine-3-carbamic acid, 10,11-dihydro-5-((dimethylamino)acetyl)-, ethyl ester, monohydrochloride
- CAS REGISTRY NUMBER :
- 78816-67-8
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C21-H25-N3-O3.Cl-H
- MOLECULAR WEIGHT :
- 403.95
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 78 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10900 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5400 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 40,871,1985