(+)-N-3-Benzyl Nirvanol

Names

[ Name ]:
(+)-N-3-Benzyl Nirvanol

[Synonym ]:
(5S)-3-benzyl-5-ethyl-5-phenylimidazolidine-2,4-dione

Biological Activity

[Description]:

(S)-(+)-N-3-Benzylnirvanol is a drug used formetabolic regulation. (S)-(+)-N-3-Benzylnirvanol has the activity of inhibitinghuman P450 enzyme. (S)-(+) -n-3-benzylnirvanol can be used to study druginteractions during drug metabolism [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. KimMJ, et al. High-throughput screening of inhibitory potential of nine cytochromeP450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.Rapid Commun Mass Spectrom. 2005;19(18):2651-8.

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Melting Point ]:
147-150ºC

[ Molecular Formula ]:
C₁₈H₁₈N₂O₂

[ Molecular Weight ]:
294.35

[ Exact Mass ]:
294.13700

[ PSA ]:
49.41000

[ LogP ]:
3.31060

[ Index of Refraction ]:
1.593

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H319-H400

[ Precautionary Statements ]:
P273-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
22-36-50

[ Safety Phrases ]:
26-61

[ RIDADR ]:
UN 3077 9/PG 3