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(3S,5S)-1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol

Names

[ CAS No. ]:
79120-40-4

[ Name ]:
(3S,5S)-1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol

[Synonym ]:
(3S,5S)-1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol
3,5-Heptanediol, 1,7-bis(4-hydroxyphenyl)-, (3S,5S)-

Biological Activity

[Description]:

Hannokinol is a potent anti-tumor agent. Hannokinol shows antiproliferative activity. Hannokinol shows antioxidant activities[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Hannokinol (compound II) (0-160 µg/mL) 显示抗增殖活性,对 SMMC-7721、HepG-2、Hela、A549 细胞的 IC50 值分别为 150.55、117.44、143.19、105.61 µg/mL[1]。

[References]

[1]. Tian-Tian Zhang, et al. Antioxidant and anti-tumour evaluation of compounds identified from fruit of Amomum tsaoko Crevost et Lemaire. Journal of Functional Foods. 2015, 18: 423-431.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
570.2±50.0 °C at 760 mmHg

[ Melting Point ]:
156-158℃ (methanol )

[ Molecular Formula ]:
C19H24O4

[ Molecular Weight ]:
316.39

[ Flash Point ]:
266.9±24.7 °C

[ Exact Mass ]:
316.167450

[ PSA ]:
80.92000

[ LogP ]:
2.32

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.616

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds