DL-Valine-d1-1

Names

[ CAS No. ]:
79168-24-4

[ Name ]:
DL-Valine-d1-1

[Synonym ]:
(RS)-<3D1>-Valine
DL-<3-(2)H>-valine
p38 MAP inhibitor III
(RS)-{4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-amine
(RS)-[2-(4-Iodphenyl)ethyl](tetrahydro-2-pyranyl)ether
2H-Pyran,tetrahydro-2-[2-(4-iodophenyl)ethoxy]

Biological Activity

[Description]:

DL-Valine-d1-1 is the deuterium labeled DL-Valine[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C5H10DNO2

[ Molecular Weight ]:
118.15

[ Exact Mass ]:
118.08500

[ PSA ]:
63.32000

[ LogP ]:
0.75460

Synthetic Route

Precursor & DownStream


Related Compounds