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7-Hydroxyaristolochic acid A

Names

[ CAS No. ]:
79185-75-4

[ Name ]:
7-Hydroxyaristolochic acid A

[Synonym ]:
7-hydroxy aristolochic acid A
9-Hydroxy-8-methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid
Phenanthro[3,4-d]-1,3-dioxole-5-carboxylic acid, 9-hydroxy-8-methoxy-6-nitro-

Biological Activity

[Description]:

7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Feng Wei, et al.Analysis of aristolochic acids and analogues in medicinal plants and their commercial products by HPLC-PAD-ESI/MS. Phytochem Anal. May-Jun 2005;16(3):222-30.

[2]. M R Rossiello, et al. Induction of hepatic nodules in the rat by aristolochic acid. Cancer Lett

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
663.7±55.0 °C at 760 mmHg

[ Melting Point ]:
287-292°C

[ Molecular Formula ]:
C17H11NO8

[ Molecular Weight ]:
357.271

[ Flash Point ]:
355.2±31.5 °C

[ Exact Mass ]:
357.048462

[ PSA ]:
131.04000

[ LogP ]:
2.47

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.776

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds