4-Methyl-4-(methyldisulfanyl)pentanoicacid

Names

[ Name ]:
4-Methyl-4-(methyldisulfanyl)pentanoicacid

[Synonym ]:
4-methyl-4-(methyldithio)pentanoic acid
Pentanoic acid,4-methyl-4-(methyldithio)
4-methyl-4-methyldisulfanylpentanoic acid
4-methyldithio-4-methyl-pentanoic acid

Biological Activity

[Description]:

4-Methyl-4-(methyldisulfanyl)pentanoic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₁₄O₂S₂

[ Molecular Weight ]:
194.31500

[ Exact Mass ]:
194.04400

[ PSA ]:
87.90000

[ LogP ]:
2.64100

4-Methyl-4-(methyldisulfanyl)pentanoicacid

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds