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Ko-3290

Names

[ CAS No. ]:
79848-61-6

[ Name ]:
Ko-3290

[Synonym ]:
Propanamide,N-[3-cyano-4-[3-[(1,1-dimethyl-2-propynyl)amino]-2-hydroxypropoxy] phenyl]-2-methyl
Koe 3290
N-(3-Cyano-4-(3-((1,1-dimethyl-2-propynyl)amino)-2-hydroxypropoxy)phenyl)-2-methylpropanamide
Ko-3290

Biological Activity

[Description]:

Ko-3290 is an antagonist of β-adrenoceptor, with cardioselectivity and antilipolytic effects in animals.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Research Areas >> Cardiovascular Disease

[References]

[1]. T.H.PRINGLE, et al. The assessment of the-3-adrenoceptor blocking activity and cardioselectivity of Koe3290 innormal subjects. British Journal of Clinical Pharmacology (1987), 24(5), 581-9


[Related Small Molecules]

Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Phenylephrine hydrochloride | Yohimbine hydrochloride | Adrenaline | Ivabradine hydrochloride | Prazosin hydrochloride | Clenbuterol hydrochloride | Phentolamine mesilate | guanfacine hydrochloride | pimozide | Sotalol hydrochloride | Carvedilol | Atenolol | Metroprolol succinate

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
583.2ºC at 760mmHg

[ Molecular Formula ]:
C19H25N3O3

[ Molecular Weight ]:
343.42000

[ Flash Point ]:
306.5ºC

[ Exact Mass ]:
343.19000

[ PSA ]:
94.38000

[ LogP ]:
2.35778

[ Storage condition ]:
2-8℃

Related Compounds