GF109

Names

[ CAS No. ]:
79873-93-1

[ Name ]:
GF109

[Synonym ]:
(1e)-3,3-bis(2-fluoroethyl)-1-(4-nitrophenyl)triaz-1-ene

Biological Activity

[Description]:

GF109 is a potent parenteral inhibitor of angiotensin converting enzyme (ACE). GF109 has antihypertensive effects[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[References]

[1]. P Hatzinikolaou, et al. Comparative study of three parenteral inhibitors of the angiotensin converting enzyme. Biochem Pharmacol. 1981 Jul 1;30(13):1869-72.  

Chemical & Physical Properties

[ Density]:
1.52g/cm3

[ Molecular Formula ]:
C10H12F2N4O2

[ Molecular Weight ]:
258.22500

[ Exact Mass ]:
258.09300

[ PSA ]:
73.78000

[ LogP ]:
3.35770

[ Index of Refraction ]:
1.704

Related Compounds