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1,2,3,6-Tetragalloylglucose

Names

[ CAS No. ]:
79886-50-3

[ Name ]:
1,2,3,6-Tetragalloylglucose

[Synonym ]:
1,2,3,6-tetrakis(O-galloyl)-β-D-glucose
1,2,3,6-tetra-O-galloyl-β-D-glucose
1(β),2,3,6-tetra-O-galloylglucose
1,2,3,6-Tetra-O-galloyl-beta-D-glucose
1,2,3,6-tetra-O-galloyl-β-D-glucopyranoside
1,2,3,6-tetrakis-O-galloyl-beta-D-glucose
1,2,3,6-tetra-O-gallolyl-β-D-glucose

Biological Activity

[Description]:

1,2,3,6-Tetragalloylglucose is a potent UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) inhibitor, with a Ki of 1.68 μM[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

Ki: 1.68 μM (UGT1A1)[1].


[References]

[1]. Park JB, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018 Oct;120:651-661.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H28O22

[ Molecular Weight ]:
788.57

[ Exact Mass ]:
788.10700

[ PSA ]:
377.42000

[ LogP ]:
0.70460

[ Storage condition ]:
2-8℃

Precursor & DownStream

Precursor

DownStream

Related Compounds