CAINDEXNAME:GUANIDINE,[(3-IODOPHENYL)METHYL]

[ Density]:
1.85g/cm3

[ Boiling Point ]:
382.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₆H₂₂I₂N₆O₄S

[ Molecular Weight ]:
648.25800

[ Flash Point ]:
184.9ºC

[ Exact Mass ]:
647.95100

[ PSA ]:
206.78000

[ LogP ]:
5.35840

[ Storage condition ]:
2-8°C

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29252900

Click to get detail synthetic route

Precursor

DownStream

Inflammatory stimuli induce inhibitory S-nitrosylation of the deacetylase SIRT1 to increase acetylation and activation of p53 and p65.

Sci. Signal. 7(351) , ra106, (2014)

Inflammation increases the abundance of inducible nitric oxide synthase (iNOS), leading to enhanced production of nitric oxide (NO), which can modify proteins by S-nitrosylation. Enhanced NO productio...

The effects of MIBG on the invasive properties of HepG2 hepatocellular carcinoma cells.

Int. J. Mol. Med. 34(3) , 842-8, (2014)

The aim of the present study was to investigate the effects of meta-iodobenzylguanidine (MIBG) on the invasive properties of hepatocellular carcinoma (HCC) cells and examine whether these effects are ...

Patient-specific dosimetry using pretherapy [¹²⁴I]m-iodobenzylguanidine ([¹²⁴I]mIBG) dynamic PET/CT imaging before [¹³¹I]mIBG targeted radionuclide therapy for neuroblastoma.

Mol. Imaging Biol. 17(2) , 284-94, (2015)

Iodine-131-m-iodobenzylguanidine ([(131)I]mIBG)-targeted radionuclide therapy (TRT) is a standard treatment for recurrent or refractory neuroblastoma with response rates of 30-40 %. The aim of this st...

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