(-)-MDO-NPA HCl

Names

[ Name ]:
(-)-MDO-NPA HCl

[Synonym ]:
(R)-MDO-NPA
(S)-Propane-1,2-diamine dihydrochloride
R-(-)-1,2-propanediamine dihydrochloride
(S)-1,2-diaminopropane
(S)-diaminopropane dihydrochloride
R(-)-10,11-Methylenedioxy-N-(n-propyl)noraporphine
(S)-1,2-propanediamine*2HCl
(S)-1,2-Diaminopropane 2HCl
S-(-)-1,2-diaminopropane dihydrochloride
(S)-1,2-Propanediamine dihydrochloride

Chemical & Physical Properties

[ Density]:
1.209g/cm3

[ Boiling Point ]:
456ºC at 760 mmHg

[ Melting Point ]:
250-252ºC

[ Molecular Formula ]:
C₂₀H₂₁NO₂

[ Molecular Weight ]:
307.38600

[ Flash Point ]:
165.2ºC

[ Exact Mass ]:
307.15700

[ PSA ]:
21.70000

[ LogP ]:
3.88550

[ Index of Refraction ]:
1.622

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Behavioral effects of (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines.

Neuropharmacology 21(10) , 953-61, (1982)

Substituted and unsubstituted 10,11-methylenedioxy derivatives of apomorphine (APO) or its N-propyl congener (NPA) were synthesized and evaluated for their ability to alter motor activity or to induce...

Dopaminergic stimulation of oxytocin concentrations in the plasma of male and female monkeys by apomorphine and a D2 receptor agonist.

J. Clin. Endocrinol. Metab. 75(3) , 855-60, (1992)

Administration of the dopamine receptor agonist apomorphine causes a dose-dependent increase in plasma oxytocin concentrations and dose-specific behavioral changes in rodents. To investigate whether d...

Tissue levels of N-n-propylnorapomorphine after treatment with (-)10,11-methylenedioxy-N-n-propylnoraporphine, an orally long-acting prodrug active at central dopamine receptors.

Neuropharmacology 21(12) , 1311-6, (1982)

High performance liquid chromatography with electrochemical detection was used to assay N-n-propylnorapomorphine (NPA) and other aporphines. Pretreatment of rats with (-)10,11-methylenedioxy-N-n-propy...