Concanamycin B

Names

[ Name ]:
Concanamycin B

[Synonym ]:
8-Deethyl-8-methylconcanamycin A
ConcanaMycin B (high purity)
L-glycero-Pentopyranose, 3-O-[4-O-(aminocarbonyl)-2,6-dideoxyhexopyranosyl]-2,4-dideoxy-1-C-[(3S)-3-[(4E,6E,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxooxacycloo ;ctadeca-4,6,14,16-tetraen-2-yl]-2-hydroxy-1-methylbutyl]-4-methyl-5-C-[(1E)-1-propen-1-yl]-, (4ξ)-
(4ξ)-3-O-(4-O-Carbamoyl-2,6-dideoxyhexopyranosyl)-2,4-dideoxy-1-C-{(4S)-4-[(4E,6E,11S,12R,13R,14E,16Z)-10,12-dihydroxy-3,17-dimethoxy-7,9,11,13,15-pentamethyl-18-oxooxacyclooctadeca-4,6,14,16-tetraen -2-yl]-3-hydroxy-2-pentanyl}-4-methyl-5-[(1E)-1-propen-1-yl]-L-glycero-pentopyranose

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
960.2±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₄₅H₇₃NO₁₄

[ Molecular Weight ]:
852.059

[ Flash Point ]:
534.5±34.3 °C

[ Exact Mass ]:
851.503113

[ PSA ]:
225.92000

[ LogP ]:
3.34

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.556

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GK6889000

CHEMICAL NAME :: Concanamycin A, 8-deethyl-8-methyl-

CAS REGISTRY NUMBER :: 81552-33-2

LAST UPDATED :: 199303

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C45-H73-N-O14

MOLECULAR WEIGHT :: 852.19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 37,1333,1984