(S)-(-)-Mosher's acid

Names

[ Name ]:
(S)-(-)-Mosher's acid

[Synonym ]:
(-)-Mosher's acid
(−)-MTPA
(S)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid
Mosher's acid
Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (αS)-
MFCD00066637
(2S)-3,3,3-Trifluoro-2-methoxy-2-phenylpropanoic acid
(S)-(-)-MTPA
(S)-Mosher's Acid
(±)-Ä-Methoxy-Ä-trifluoromethylphenylacetic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
287.2±0.0 °C at 760 mmHg

[ Melting Point ]:
41-46ºC(lit.)

[ Molecular Formula ]:
C₁₀H₉F₃O₃

[ Molecular Weight ]:
234.172

[ Flash Point ]:
134.2±27.3 °C

[ Exact Mass ]:
234.050385

[ PSA ]:
46.53000

[ LogP ]:
3.79

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.470

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Anti-complement sesquiterpenes from Viola yedoensis.

Fitoterapia 101 , 73-9, (2015)

Two new germacrane sesquiterpenes, yedoensins A (1) and B (2), together with 8 known ones (3-10) were isolated from the herb of Viola yedoensis. The structures of the new compounds were established by...

a-Methoxy-a-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines. J. A. Dale, D. L. Dull, H. S. Mosher

J. Org. Chem. 34(9) , 2543-2549, (1969)