2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro-
Names
[ CAS No. ]:
82023-29-8
[ Name ]:
2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro-
[Synonym ]:
3-Pfu
N3-phthalidyl-5-fluorouracil
Uracil,5-fluoro-3-phthalidyl
5-Fluoro-3-phthalidyl-uracil
Chemical & Physical Properties
[ Density]:
1.62g/cm3
[ Molecular Formula ]:
C12H7FN2O4
[ Molecular Weight ]:
262.19300
[ Exact Mass ]:
262.03900
[ PSA ]:
81.42000
[ LogP ]:
0.80530
[ Index of Refraction ]:
1.664
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YR0430000
- CHEMICAL NAME :
- Uracil, 5-fluoro-3-phthalidyl-
- CAS REGISTRY NUMBER :
- 82023-29-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C12-H7-F-N2-O4
- MOLECULAR WEIGHT :
- 262.21
- WISWESSER LINE NOTATION :
- T56 BVO DHJ D- CT6MVNVJ EF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,1219,1982