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Acetyl tetrapeptide-5

Names

[ CAS No. ]:
820959-17-9

[ Name ]:
Acetyl tetrapeptide-5

[Synonym ]:
N-Acetyl-β-alanyl-L-histidyl-L-seryl-l-histidin
UNII-Y1DFQ308G8
Eyeseryl
L-Histidine, N-acetyl-β-alanyl-L-histidyl-L-seryl-
N-Acetyl-β-alanyl-L-histidyl-L-seryl-L-histidine
Acetyl tetrapeptide-5

Biological Activity

[Description]:

Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care[1][2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[Target]

ACE-1[1]


[In Vitro]

Acetyl tetrapeptide-5 (100 μg/mL) inhibits angiotensin-converting enzyme 1 (ACE-1) activity[1].

[References]

[1]. Yun Wu, et al. Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts. Skin Pharmacol Physiol. 2021;34(4):194-202.

[2]. Lijuan Zhang, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009 Sep-Oct;27(5):485-94.

[3]. Puig A , et al. "Eyeseryl® and Leuphasyl®: synthetic peptides as advanced cosmetic actives. Cosmet Sci Technol (2006): 164-75.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1237.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H28N8O7

[ Molecular Weight ]:
492.486

[ Flash Point ]:
702.1±34.3 °C

[ Exact Mass ]:
492.208099

[ PSA ]:
245.25000

[ LogP ]:
-3.79

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.611

[ Storage condition ]:
2-8℃

Related Compounds