DL-Leucine-1-13C

Names

[ Name ]:
DL-Leucine-1-13C

[Synonym ]:
Leucine-1-C
MFCD00064041
(1-C)Leucine
DL-Leucine-1-13C

Biological Activity

[Description]:

(±)-Leucine-13C-1 (DL-Leucine-13C-1) is the 13C-labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Hendricks DE, et, al. Attractiveness of tobacco budworm females altered by oral chemosterilants and dietary additives. Journal of Chemical Ecology. 1977 Mar; 127-131.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Melting Point ]:
293-296ºC (subl.)(lit.)

[ Molecular Formula ]:
C₆H₁₃NO₂

[ Molecular Weight ]:
132.166

[ Exact Mass ]:
132.097977

[ PSA ]:
63.32000

[ LogP ]:
1.14470

[ Index of Refraction ]:
1.463

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport