GYKI 51189
Names
[ CAS No. ]:
82230-53-3
[ Name ]:
GYKI 51189
[Synonym ]:
Girisopam [INN]
1-(3-Chlorophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine
Girisopamum [INN-Latin]
1-(3-Chlorphenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin
1-(m-Chlorophenyl)-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine
[3H]-Girisopam
5H-2,3-Benzodiazepine,1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl
Girisopam
Chemical & Physical Properties
[ Density]:
1.23g/cm3
[ Boiling Point ]:
453.9ºC at 760 mmHg
[ Molecular Formula ]:
C18H17ClN2O2
[ Molecular Weight ]:
328.79300
[ Flash Point ]:
228.3ºC
[ Exact Mass ]:
328.09800
[ PSA ]:
43.18000
[ LogP ]:
2.99780
[ Index of Refraction ]:
1.598
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DE9480200
- CHEMICAL NAME :
- 5H-2,3-Benzodiazepine, 1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-
- CAS REGISTRY NUMBER :
- 82230-53-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H17-Cl-N2-O2
- MOLECULAR WEIGHT :
- 328.82
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987