Etomoxir (Na salt)

Names

[ Name ]:
Etomoxir (Na salt)

[Synonym ]:
Sodium (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylate
2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt, (2R)- (1:1)
cc-140
(+)-Etomoxir (sodium salt)
ANTI-EAPII(TTRAP)
(2R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid sodium salt
MFCD07787411
(+)-Etomoxir sodium salt
(R)-(+)-Etomoxir (sodium salt)

Biological Activity

[Description]:

(R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

CPT-1[1]

[In Vitro]

(R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig[1].

[References]

[1]. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₈ClNaO₄

[ Molecular Weight ]:
320.744

[ Exact Mass ]:
320.079132

[ PSA ]:
61.89000

[ LogP ]:
2.18820

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
22

[ RIDADR ]:
UN 2811 6.1/PG 3