Euquinine

Names

[ CAS No. ]:
83-75-0

[ Name ]:
Euquinine

[Synonym ]:
Euquinin
Quinine,ethyl carbonate (ester) (6CI,7CI,8CI)
Euquinine (Euchinin)
9-ethoxycarbonyloxy-6'-methoxy-cinchonane
Kohlensaeure-aethylester-((8S,9R)-6'-methoxy-cinchonan-9-ylester)
QUININE ETHYL CARBONATE
Euchinine
QUININE CARBONIC ETHER
ethyl quinine carbonate
Euquinin (Euchinin)
tastless quinine

Biological Activity

[Description]:

Euquinine is an odorless salt that can be used asa substitute for quinine. Euquinine has anti-Plasmodium falciparum activity.Euquinine can be used for the study of multidrug resistance and bioavailabilityof Plasmodium falciparum [1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Jamaludin A, et al. Relative bioavailability of the hydrochloride, sulphate and ethyl carbonate salts of quinine. Br J Clin Pharmacol. 1988 Feb;25(2):261-3.

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
526.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₃H₂₈N₂O₄

[ Molecular Weight ]:
396.48

[ Flash Point ]:
272.1ºC

[ Exact Mass ]:
396.20500

[ PSA ]:
60.89000

[ LogP ]:
4.29190

[ Index of Refraction ]:
1.6

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%