(-)-Epigallocatechin-3-(3''-O-methyl) gallate

Names

[ Name ]:
(-)-Epigallocatechin-3-(3''-O-methyl) gallate

[Synonym ]:
(2R,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4-dihydroxy-5-methoxybenzoate
UNII-O97U9TPY8V
Benzoic acid, 3,4-dihydroxy-5-methoxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
Egcg3''me
(-)-EGCG-3''-O-Me
Epigallocatechin 3-O-(3-O-methyl)gallate

Biological Activity

[Description]:

(-)-Epigallocatechin-3-(3''-O-methyl) gallate is a natural product isolated from the tea leaf, with strong antioxidative activity. (-)-Epigallocatechin-3-(3''-O-methyl) gallate has a strong cytotoxic activity for rat cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Kawase M, et al. Antioxidative activity of (-)-epigallocatechin-3-(3''-O-methyl)gallate isolated from fresh tea leaf and preliminary results on its biological activity. Biosci Biotechnol Biochem. 2000 Oct;64(10):2218-20.

Chemical & Physical Properties

[ Density]:
1.77

[ Boiling Point ]:
856.1±65.0 °C at 760 mmHg

[ Melting Point ]:
221-223 ºC(dec.)

[ Molecular Formula ]:
C₂₃H₂₀O₁₁

[ Molecular Weight ]:
472.398

[ Flash Point ]:
298.9±27.8 °C

[ Exact Mass ]:
472.100555

[ PSA ]:
186.37000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.796

(-)-Epigallocatechin-3-(3''-O-methyl) gallate

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds