Dynorphin (2-17) (porcine)

Names

[ CAS No. ]:
83608-80-4

[ Name ]:
Dynorphin (2-17) (porcine)

[Synonym ]:
DynA 2-17
DYNORPHIN A (2-17)

Biological Activity

[Description]:

Dynorphin (2-17) (porcine) is a peptide derived from Prodynorphin, can improve somatic signs of Morphine-dependent withdrawal[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vivo]

Dynorphin (2-17) treatment reduces Naloxone-precipitated withdrawal signs in Morphine-dependent rats[1]. Animal Model: Male Sprague Dawley rats implanted with Morphine[1] Dosage: 0.1-5.0 mg/kg Administration: Intravenous injection; 0.1-5.0 mg/kg; once Result: Attenuated the incidence of wet dog shakes after Naloxone injection 30 min. Decreased Naloxone-induced body weight loss.

Chemical & Physical Properties

[ Molecular Formula ]:
C90H146N30O21

[ Molecular Weight ]:
1984.31000

[ Exact Mass ]:
1983.13000

[ PSA ]:
868.04000

[ LogP ]:
5.69250

Related Compounds