Antimalarial agent 1

Names

[ Name ]:
Antimalarial agent 1

[Synonym ]:
EINECS 282-331-2
6,7-diisopropylpteridine-2,4-diamine phosphate
MFCD00012733
2,4-diamino-6,7-diisopropylpteridine phosphate
6,7-Bis(1-Methylethyl)-2,4-pteridinediaMine Phosphate

Biological Activity

[Description]:

Antimalarial agent 1 is a potent antimalarial drug[1].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

Antimalarial agent 1 has an antimalarial index of 1:40, when tested against Plasmodium gallinaceum[1].

[References]

[1]. MCCONNACHIE EW, et al. The action of 2:4-diamino-6:7-diisopropylpteridine on normal, proguanil- and sulphadiazine-resistant strains of Plasmodium gallinaceum. arasitology. 1953 Jan;42(3-4):272-6.

Chemical & Physical Properties

[ Boiling Point ]:
441.8ºC at 760 mmHg

[ Melting Point ]:
232-234ºC(lit.)

[ Molecular Formula ]:
C₁₂H₂₁N₆O₄P

[ Molecular Weight ]:
344.30700

[ Flash Point ]:
251.2ºC

[ Exact Mass ]:
344.13600

[ PSA ]:
191.17000

[ LogP ]:
2.06480

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3