IMAZODAN

Names

[ Name ]:
IMAZODAN

[Synonym ]:
Imazodanum
Cl 914
Imazodanum [Latin]
IMAZODAN
4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinone
3(2H)-Pyridazinone,4,5-dihydro-6-(4-(1H-imidazol-1-yl)phenyl)
MFCD00867109
Imazodan [INN]

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Molecular Formula ]:
C₁₃H₁₂N₄O

[ Molecular Weight ]:
240.26100

[ Exact Mass ]:
240.10100

[ PSA ]:
59.28000

[ LogP ]:
1.25080

[ Index of Refraction ]:
1.696

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

New mechanisms for positive inotropic agents: focus on the discovery and development of imazodan.

Cardiovasc. Drugs Ther. 3(1) , 29-42, (1989)

Intense efforts during the last decade to identify a useful positive inotropic agent to replace digitalis for the treatment of congestive heart failure have led to the discovery of several dozen poten...

Determination of 4,5-dihydro-6-[4-(1H-imidazol-1-yl) phenyl]-3(2H)-pyridazinone hydrochloride, a new cardiotonic, in plasma and urine by reversed-phase high-performance liquid chromatography.

J. Chromatogr. A. 336(2) , 446-51, (1984)

Effect of a new phosphodiesterase type III inhibitor as a coronary vasodilator and positive inotropic agent.

Cardiovasc. Res. 21(8) , 593-600, (1987)

Isolated rabbit coronary arteries, aortic strips, and a working rabbit heart preparation were used to assess the positive inotropic and vasodilator effects of a newly developed positive inotropic comp...