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Rosarin

Names

[ CAS No. ]:
84954-93-8

[ Name ]:
Rosarin

[Synonym ]:
(2E)-3-Phenylprop-2-en-1-yl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
MFCD04039808
(2E)-3-Phenyl-2-propen-1-yl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
β-D-Glucopyranoside, (2E)-3-phenyl-2-propen-1-yl 6-O-α-L-arabinofuranosyl-
Rosarin

Biological Activity

[Description]:

Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in the kidney and prefrontal cortex of brain in mice [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vitro]

Rosarin (0-50 μg/ml; 18 hours) pretreats 30 mins in LPS-induced BV-2 cells supresses iNOS and cytokines expression in a concentration-dependent manner in the murine BV2 cells[1].

[References]

[1]. Lee Y, et al. Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.Evid Based Complement Alternat Med. 2013;2013:514049.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
730.8±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H28O10

[ Molecular Weight ]:
428.430

[ Flash Point ]:
395.8±32.9 °C

[ Exact Mass ]:
428.168243

[ PSA ]:
158.30000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.635

[ Storage condition ]:
2-8°C

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Precursor & DownStream

Precursor

DownStream

Related Compounds