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ARP 101

Names

[ CAS No. ]:
849773-63-3

[ Name ]:
ARP 101

[Synonym ]:
arp 101

Biological Activity

[Description]:

ARP101 is a potent and selective inhibitor matrix metalloproteinase-2 (MMP-2). ARP101 induces autophagy-associated cell death in cancer cells. ARP101 is effective in inducing the formation of autophagosome and conversion of LC3I into LC3II[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[References]

[1]. Jo YK, et al. ARP101, a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells. Biochem Biophys Res Commun. 2011;404(4):1039-1043.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H26N2O5S

[ Molecular Weight ]:
406.49600

[ Exact Mass ]:
406.15600

[ PSA ]:
104.32000

[ LogP ]:
4.68600


Related Compounds