Acetrizoic Acid

Names

[ CAS No. ]:
85-36-9

[ Name ]:
Acetrizoic Acid

[Synonym ]:
MFCD00016495
3-(acetylamino)-2,4,6-triiodobenzoic acid
Benzoic acid, 3-(acetylamino)-2,4,6-triiodo-
EINECS 201-600-7
UNII:24256BQV7M
3-Acetamido-2,4,6-triiodobenzoic acid

Biological Activity

[Description]:

Acetrizoic acid is a molecule used as a contrast medium.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[References]

[1]. CHEN Xing-ming, et al. Comparison of side effects between acetrizoic acid and omnipaque during interventional therapy. Journal of Foshan University (Natural Science Edition), 2008-06

[2]. LV Xiao-qin, et al. Statistical Analysis of 153 Cases Manifesting Adverse Reactions Caused by Acetrizoic Acid. Chinese Journal of Modern Applied Pharmacy, 2008-01

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
2.8±0.1 g/cm3

[ Boiling Point ]:
547.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₆I₃NO₃

[ Molecular Weight ]:
556.862

[ Flash Point ]:
284.7±30.1 °C

[ Exact Mass ]:
556.748169

[ PSA ]:
66.40000

[ LogP ]:
1.04

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.802

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG0887000

CHEMICAL NAME :: Benzoic acid, 3-acetamido-2,4,6-triiodo-

CAS REGISTRY NUMBER :: 85-36-9

BEILSTEIN REFERENCE NO. :: 2219129

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H6-I3-N-O3

MOLECULAR WEIGHT :: 556.86

WISWESSER LINE NOTATION :: QVR BI DI FI CMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9650 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 42,721,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 18,33,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 18,33,1963

Safety Information

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ RTECS ]:
DG0887000

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%