Bis-acrylate-PEG6

Names

[ Name ]:
Bis-acrylate-PEG6

[Synonym ]:
EINECS 285-782-3
2-Propenoic acid,1,1'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diyl) ester
2-Propenoicacid,3,6,9,12,15-pentaoxaheptadecane-1,17-diyl ester (9CI)
Hexaethyleneglycoldiacrylate
3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl diacrylate

Biological Activity

[Description]:

Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Density]:
1.101g/cm3

[ Boiling Point ]:
459.125ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₃₀O₉

[ Molecular Weight ]:
390.42500

[ Flash Point ]:
196.816ºC

[ Exact Mass ]:
390.18900

[ PSA ]:
98.75000

[ LogP ]:
0.52780

[ Index of Refraction ]:
1.46

Safety Information

[ Hazard Codes ]:
Xi

Bis-acrylate-PEG6

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds