BI Compound D

A potent non-nucleoside RSV L-protein polymerase inhibitor with IC50 of 89 nM; shows anti-RSV activity with IC50 of 57.6 nM and 47.8 nM for RSV A2 and RSV B-EST, respectively; shows weak cytotoxicity (CC50=600 nM).

References 1. Liuzzi M, et al. J Virol. 2005 Oct;79(20):13105-15. 2. Mason SW, et al. Nucleic Acids Res. 2004 Sep 8;32(16):4758-67. 3. Coates M, et al. Antimicrob Agents Chemother. 2017 Jun 26. pii: AAC.00737-17. View Related Products by Target RSV