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WAY-354574

Names

[ CAS No. ]:
851873-40-0

[ Name ]:
WAY-354574

[Synonym ]:
Benzamide, N-[(3-chlorophenyl)methyl]-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-

Biological Activity

[Description]:

WAY-354574 is an active molecule targeting deacetylase (Sirtuin) for the study of Huntington's disease (HD)[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin
Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin
Research Areas >> Neurological Disease

[Target]

Sirtuin-2 (SIRT2)[1]


[References]

[1]. Khanfar MA, et al. Development and characterization of 3-(benzylsulfonamido)benzamides as potent and selective SIRT2 inhibitors. Eur J Med Chem. 2014 Apr 9;76:414-26.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H23ClN2O3S

[ Molecular Weight ]:
406.92622


Related Compounds