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ML031

Names

[ CAS No. ]:
852230-33-2

[ Name ]:
ML031

[Synonym ]:
2,5-Pyrrolidinedione, 1-[2-[2,5-dimethyl-1-(phenylmethyl)-1H-pyrrol-3-yl]-2-oxoethyl]-
1-[2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethyl]-2,5-pyrrolidinedione

Biological Activity

[Description]:

CYM-5482 is a potent and selective agonist Sphingosine 1-phosphate receptor 2 (S1PR2) with an IC50 and EC50 of 1.0 and 1.03 μM. CYM-5482 has the potential for the research of cancer diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> LPL Receptor

[References]

[1]. Satsu H, et al. A sphingosine 1-phosphate receptor 2 selective allosteric agonist. Bioorg Med Chem. 2013;21(17):5373-5382.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
568.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H20N2O3

[ Molecular Weight ]:
324.374

[ Flash Point ]:
297.8±30.1 °C

[ Exact Mass ]:
324.147400

[ PSA ]:
59.38000

[ LogP ]:
1.95

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.617

Synthetic Route

Click to get detail synthetic route